Purpose: This study aimed to investigate longitudinal associations of objectively measured physical activity (PA) and sedentary behavior (SB) with body composition and physical fitness at
Objectives: (1) To examine whether cardiorespiratory fitness (CRF) is related to liver enzyme levels independent of waist circumference (WC), and (2) To test whether having
Background: Traditional obesity prevention programs are time-and cost-intensive. Mobile phone technology has been successful in changing behaviors and managing weight; however, to our knowledge, its
Objectives: To examine the associations of physical fitness (i.e. cardiorespiratory fitness, muscular strength, and speed/agility) with psychological distress and psychological well-being in overweight/obese pre-adolescent children.
Background & aims: Chronobiology studies periodic changes in living organisms and it has been proposed as a promising approach to investigate obesity. We analyze the
The aims of the present article are to systematically review and meta-analyze the existing evidence on: 1) differences in physical activity (PA), sedentary behavior (SB),
Indirect calorimetry (IC) is considered the reference method to determine the resting energy expenditure (REE), but its use in a clinical context is limited. Alternatively,
The aim of this study was to evaluate the effect of sitagliptin on glucose tolerance, plasma lipids, energy expenditure and metabolism of brown adipose tissue
Human brown adipose tissue (BAT) has attracted clinical interest not only because it dissipates energy but also for its potential capacity to counteract obesity and
Having valid and reliable resting energy expenditure (REE) estimations is crucial to establish reachable goals for dietary and exercise interventions. However, most of the REE
Cold induced thermogenesis (CIT) in humans results mainly from the combination of both brown adipose tissue (BAT) and skeletal muscle thermogenic activity. The relative contribution
Purpose To examine the adherence to the Mediterranean dietary pattern (MDP) in metabolically healthy overweight or obese (MHO) and metabolically unhealthy obese (MUO) European adolescents.
Background & aims: Since the discovery of active brown adipose tissue in human adults, non-shivering cold-induced thermogenesis (CIT) has been regarded as a promising tool
The alpha-Klotho gene was identified as a possible “aging-suppressor” agent that extends life span when overexpressed. However, little is known about the association of the
Obesity is a major risk factor for obstructive sleep apnoea (OSA), the most common sleep-disordered breathing related to neurocognitive and metabolic syndromes, type II diabetes,
The present study examines whether the daily rhythm of distal skin temperature (DST) is associated with brown adipose tissue (BAT) metabolism as determined by F-18-fluorodeoxyglucose
Obesity and insulin resistance have been recognised as leading causes of major health issues, particularly diabetes type 2 and metabolic syndrome. Although obesity, defined as
Objective: To determine reference values for body mass index (BMI), sum of six skinfolds (Sigma 6 skinfolds) and body fat percentage (BF%) in Spanish adolescents
Regulation of energy homeostasis requires precise coordination between peripheral nutrient-sensing molecules and central regulatory networks. Ghrelin is a twenty-eight-amino acid orexigenic peptide acylated at the
White adipose tissue functions not only as an energy store but also as an important endocrine organ and is involved in the regulation of many
Aims/hypothesis Our aim was to examine the association between markers of insulin resistance and: (1) body fat and waist circumference, taking into account cardiorespiratory fitness
Objectives: To identify the main knowledge gaps and to propose research lines that will be developed within the European Union-funded ‘Healthy Lifestyle in Europe by
The MS (metabolic syndrome) is a cluster of clinical and biochemical abnormalities characterized by central obesity, dyslipidaemia [hypertriglyceridaemia and decreased HDL-C (high-density lipoprotein cholesterol)], glucose
Objectives: To describe the anthropometric profile and body composition ofwomenfrom Southern Spain diagnosed with fibromyalgia (FM) and to compare the observed values with values from
Objective. This study was to examine the influence of socioeconomic status on fitness and fatness in Spanish adolescents. Subjects and Methods. A total of 1
Objective: The objective of this study was to examine the association of birth weight (BW) with body composition, resting metabolic rate (RMR), nonprotein respiratory quotient
The aim of the present study was to investigate the association of PLIN1 114820 > A (rs894160) and PLIN1 13041A > G (rs2304795) polymorphisms with
The authors’ aim in this cross-sectional study was to characterize levels of objectively measured physical activity and sedentary time in adolescents from 9 European countries.
Objective. The goal of the present study was to assess the relationship between the genetic variability in six genes of methyl group (CH(3)) metabolism and
Background/Aims: There is a strong debate on the diagnosis and early phenotypic expression of the metabolic syndrome in children. The aim of the present study
ORTEGA, F. B., I. LABAYEN, J. R. RUIZ, E. KURVINEN, H.-M. LOIT, J. HARRO, T. VEIDEBAUM, and M. SJOSTROM. Improvements in Fitness Reduce the Risk
Overweight and obesity are the epidemics of the 21st century in developed countries. Obesity is associated with several metabolic disorders and various diseases such as
Objective: This study aimed to examine the association of television (TV) time, the frequency of meals while watching TV and the presence of TV set
Background: We examined the association of cardiorespiratory fitness and fatness with health complaints and health risk behaviors in 691 (323 girls) Spanish children aged 6
Digestible carbohydrates are one of the main sources of dietary energy in infancy and childhood and are essential for growth and development. The aim of
The aim of this study was to explore the effects of a multidisciplinary behavioral intervention including cognitive behavioral therapy, structured physical activity, and dietary counseling
Background/Aims: We studied the effect of a 12-week energy-restricted diet intervention on cardiometabolic risk in two groups of nonmorbid obese premenopausal Caucasian women, i.e. a
Current knowledge on the prognosis of metabolically healthy but obese phenotype is limited due to the exclusive use of the body mass index to define
What is already known about this subject There is an association between adiposity levels and physical activity guidelines for adolescents. Achieving physical activity recommendations helps
Evidence has grown supporting the role for short sleep duration as an independent risk factor for weight gain and obesity. The purpose of the present
Introduction: “Obesity” is considered a feature of youth with DS but whether “low physical fitness” is also a feature is unknown. Objective: The aim of
Variants in the neuropeptide Y (NPY) gene have been associated with obesity and its traits. The objective of the present study was to evaluate the
Changes in paraoxonase 1 (PON1) activities have been observed in a variety of diseases involving oxidative stress, such as CVD. However, its role in obesity
Aim: The aim of this study is to measure objectively and accurately the physical activity (PA) patterns in Spanish children and adolescents according to their
Background/Aims: Altered expression and activity of the antioxidant enzymes glutathione peroxidases (GPXs) have been observed in obesity in human and animal studies. We aimed to
Background: Variants in the FTO gene have been associated with obesity in children, but this association has not been shown with other biomarkers. We assessed
OBJECTIVE: Coordinated European projects relying on standardized methods are needed to identify health inequalities across Europe. This study aimed to compare fitness, fatness, and cardiometabolic
Obesity is a multifactorial disease characterized by the excessive accumulation of fat in adipose tissue and peripheral organs. Its derived metabolic complications are mediated by
Introduction: In the physical education context a well-known myth suggest that obese and unfit youth dislike physical education. Objective: To examine if adolescents who dislike
Background: The energy-burning capacity of brown adipose tissue (BAT) makes it an attractive target for use in anti-obesity therapies. Moreover, due to its ability to
Background/Aims: We aimed to evaluate the use of a continuous metabolic syndrome (MetS) score and to assess the associations of this score with risk biomarkers
Early menarche has been associated with adult overweight, cardiovascular risk factors, and other diseases. Little is known about the determinants of menarcheal age (MA). Therefore,
Introduction and objectives: the overall intake of a cohort of middle aged women of Granada was studied along with their body composition, anthropometric and sociodemographic
Aim: Current physical activity (PA) recommendations indicate that children should get involved in 60 minutes of moderate-to-vigorous PA (MVPA), and should include vigorous-intensity PA at
Characterization of the genes expressed in adipose tissue (AT) is key to understanding the pathogenesis of obesity and to developing treatments for this condition. Our
Weight gain and obesity are a important problems in breast cancer patients. A cross-sectional study was conducted with 147 BCSs. This study demonstrated the influence
Background: The consumption of orange juice may lead to reduced oxidative stress and may enhance the antioxidant defense system. Objective: The aim was to evaluate
Background: Non-alcoholic fatty liver disease is the most frequent liver abnormality observed in overweight or obese children and is strongly associated with metabolic syndrome and
Aims: The energy expenditure capacity of brown adipose tissue (BAT) makes it an attractive target as a therapy against obesity and type 2 diabetes. BAT
Objectives: This study aimed to explore the associations of liver biomarkers with cardiometabolic risk factors and their clustering, and to provide reference values (percentiles) and
The prevalence of obesity has increased worldwide over the past few decades. In 2013, the prevalence of obesity exceeded the 50% of the adult population
Introduction: There is a lack of information about fitness and other health indicators in women from countries such as Morocco. This study aims to explore
The prevalence and severity of obesity have increased in the United States and most of the Westernized World over recent decades, reaching worldwide epidemics. Since
Over the last several years, the increasing prevalence of obesity has favored an intense study of adipose tissue biology and the precise mechanisms involved in
The use of probiotics and synbiotics in the prevention and treatment of different disorders has dramatically increased over the last decade. Both probiotics and synbiotics
The present study was undertaken to investigate the effects of C-atrial natriuretic peptide (C-ANP(4-23)) in human adipose-derived stem cells differentiated into adipocytes over 10 days
Background: Overweight and obesity are considered to be serious public health problems. In pediatric populations, insulin resistance, dyslipidemia, and hypertension associated with obesity occur with
Objectives: To investigate whether health-related physical fitness is associated with total and central body fat in preschool children. Methods: A total of 403 Spanish children
Background: There are critical periods during pregnancy and early life when child’s neurodevelopment can be altered, where different factors including hormones, stress, genetics, and diet
Background: Weight loss is a public health concern in obesity-related diseases such as metabolic syndrome, and the protein level of the diets seem to be
Background and aims: The fat mass and obesity associated gene (FTO) has been associated with obesity and dietary intake. The aims were: (i) To assess
Background: The risk for major depression and obesity is increased in adolescents and adults with attention-deficit / hyperactivity disorder (ADHD) and adolescent ADHD predicts adult
Overweight and obesity have reached epidemic levels in the United States and worldwide, and this has contributed to substantial cardiovascular and other health risks. However,
