Background: physical inactivity and unhealthy nutrition behaviours in early ages are two of the biggest problems related with public health in developed countries. Aims: to carry out a systematic review of school-based programs related with physical activity promotion and/or nutrition in adolescents implemented in Spain and published in the principal national and international data bases in the last 15 years. Method: the literature was searched in spanish and english data bases Web of Science, ERIC, PsycINFO, Dialnet and ISOC, following PRISMA declaration principles for systematic reviews. Results and discussion: from a total of 522 references, were retained 13 studies due to inclusion criteria. The most prevalent programs included families participation in the intervention. At the same time, the Physical Education teachers and the health personnel were the principal actor in programs development. Both of them were the principal protagonist in interventions. All the programs were able to improve at least one of the variables. Conclusion: were identified only 13 school-based intervention programs related with physical activity and/or nutrition in adolescents in the last 15 years in Spain. All the programs reached improvements, so school shows a relevant role in acquisition or improvement of this health behavior.