Publicación

Do women with fibromyalgia present higher cardiovascular disease risk profile than healthy women? The al-Andalus project

  • CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Autores
    Acosta-Manzano, P; Segura-Jimenez, V; Estevez-Lopez, F; Alvarez-Gallardo, IC; Soriano-Maldonado, A; Borges-Cosic, M; Gavilan-Carrera, B; Delgado-Fernandez, M; Aparicio, VA
  • Año Publicación
    2017
  • Volumen
    35
  • Número
    3
  • Pág. Inicio
    S61
  • Pág. Fin
    S67
  • Pág. Fin
    S61
DOI

Objective. To analyse the cardiovascular disease risk profile of women with fibromyalgia and compare it with control women; and to test whether physical activity is associated with the cardiovascular disease risk profile in this population. Methods. This cross-sectional study comprised 436 women with fibromyalgia (51.4 +/- 7.5 years old) and 217 controls (48.4 +/- 9.6 years old) from Andalusia, Spain. Clinical data, waist circumference, body fat percentage, resting heart rate, blood pressure and cardiorespiratory fitness were assessed. Moderate-to-vigorous physical activity was objectively assessed with accelerometry. A clustering of individual cardiovascular disease risk factors was represented by the number of cigarettes/day, adiposity, mean arterial pressure, resting heart rate and cardiorespiratory fitness. Results. Women with fibromyalgia presented higher waist circumference and body fat percentage, greater number of cigarettes/day consumption and lower levels of cardiorespiratory fitness after controlling for age, marital status, educational level, occupational status, medication for cholesterol and monthly regular menstruation (all, p<0.05). Women with fibromyalgia showed higher clustered cardiovascular disease risk than control women after controlling for the potential confounders described above (p<0.001). Women with fibromyalgia who did not meet moderate-to-vigorous physical activity recommendations showed increased clustered cardiovascular disease risk after adjusting for the potential confounders described above (p<0.001). Conclusion. Women with fibromyalgia may present higher risk of cardiovascular disease than controls. Inadequate levels of moderate-to-vigorous physical activity may play a significant role as an additional predisposing factor for cardiovascular disease risk in this population.


Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UG

Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UGR