Publicación

Physical activity attenuates the negative effect of low birth weight on leptin levels in European adolescents; The HELENA study

  • NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
  • Autores
    Labayen, I; Ortega, FB; Moreno, LA; Gonzalez-Gross, M; Jimenez-Pavon, D; Martinez-Gomez, D; Breidenassel, C; Marcos, A; Molnar, D; Manios, Y; Plada, M; Kafatos, A; De Henauw, S; Mauro, B; Zaccaria, M; Widhalm, K; Gottrand, F; Castillo, MJ; Sjostrom, M; Ruiz, JR
  • Año Publicación
    2013
  • Volumen
    23
  • Número
    4
  • Pág. Inicio
    344
  • Pág. Fin
    349
  • Pág. Fin
    344
Referencia Citadas
23
Citas Web of Science
8
Total de veces citado (Z9)
8
Recuento Uso 5 años
27

We examined whether physical activity (PA) influences the association between birth weight and serum leptin in adolescents. The study comprised a total of 538 adolescents (315 girls), aged 12.5-17.49 years, born at term (>= 37 weeks of gestation). We measured serum leptin levels and time engaged in moderate-vigorous PA (MVPA) by accelerometry. There was an interaction effect between birth weight and meeting the PA recommendations (60 min/day MVPA) on leptin levels in girls (P = 0.023) but not in boys (P = 0.809). Birth weight was negatively associated with leptin levels in girls not meeting the PA recommendations (i.e. more than 60 min/day of MVPA) (beta = -0.096, P = 0.009), whereas no significant association was observed in those meeting the PA recommendations (beta = -0.061, P = 0.433). In conclusion, meeting the PA recommendations may attenuate the negative effect of low birth weight on serum leptin levels in European female adolescents. (C) 2012 Elsevier B.V. All rights reserved.


Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UG

Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UGR