Publicación

A multimodal exercise program and multimedia support reduce cancer-related fatigue in breast cancer survivors: A randomised controlled clinical trial

  • EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
  • Autores
    Cantarero-Villanueva, I; Fernandez-Lao, C; Diaz-Rodriguez, L; Fernandez-de-las-Penas, C; del Moral-Avila, R; Arroyo-Morales, M
  • Año Publicación
    2011
  • Volumen
    3
  • Número
    3
  • Pág. Inicio
    E189
  • Pág. Fin
    E200
  • Pág. Fin
    E189
Referencia Citadas
60
Citas Web of Science
20
Total de veces citado (Z9)
20
Recuento Uso 180 días
1
Recuento Uso 5 años
31

Aim of the study: To evaluate the effects of an 8-week multimodal physical therapy program with multimedia support on cancer-related fatigue, cortisol and IgA salivary concentrations, alpha-amylase activity and neck-shoulder mobility, in breast cancer. Methods: This was a prospective randomised clinical trial using between-groups design. Seventy-eight breast cancer survivors during first year after treatment participated. Participants were assigned into 2 groups: CUIDATE group (multimodal program) or control group (usual care). CUIDATE program consisted of 24 h of individual physical training and 12 h of stretching and massage interventions. Measurements included the Piper Fatigue Scale, cortisol and IgA salivary levels, alpha-amylase activity and active cervical-shoulder range of motion. Results: Compared to the control group, CUIDATE group showed a estimated improvement for total fatigue score of -2.49 points immediately after treatment (between-group effect size 0.68; P < 0.001) and -1.43 at 6 month follow-up (between group effect size: 0.43; P < 0.01). CUIDATE group showed a decrease in alpha-amylase activity of -41.77 U/ml immediately after treatment compared to the control group (between-group effect size: 0.24; P = 0.046). Further, significant between-group improvements for shoulder flexion, horizontal abduction, cervical extension and lateral-flexion (between-group effect sizes ranging 0.30-0.75; all P < 0.05) after treatment were also found. Conclusions: An 8-week multimodal physical therapy program was effective at short and 6 month follow-up for decreasing fatigue in breast cancer survivors. The program was also effective in decreasing alpha-amylase activity and improving shoulder and cervical range of motion. (C) 2011 Elsevier GmbH. All rights reserved.


Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UG

Web financiada por la Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, Fondo Europeo de Desarrollo Regional (FEDER), proyecto SOMM17/6107/UGR